Hereditary spastic paraplegia

Neuromuscular disorders affect your neuromuscular system. They can cause problems withThe nerves that control your musclesYour musclesCommunication between your nerves and musclesThese disorders can cause your muscles to become weak and waste away. You may also have symptoms such as spasms, twitching, and pain.Examples of neuromuscular disorders includeAmyotrophic lateral sclerosisMuscular dystrophyMyasthenia gravisSpinal muscular atrophyThere can be different causes for these diseases. Many of them are genetic.This means they are inherited (run in families) or are caused by a new mutation in your genes. Some neuromuscular disorders are autoimmune diseases. Sometimes the cause is not known.Many neuromuscular diseases have no cure. But treatments may improve symptoms, increase mobility, and lengthen life.