Hemophagocytic syndrome
A classification of rare, non-neoplastic, proliferative disorders of the hematologic system. Primary or familial hemophagocytic lymphohistiocytosis (HLH) is inherited with an autosomal recessive pattern with five known subtypes differentiated by specific genetic mutations. Secondary manifestation of HLH is usually seen in hyperactivated immunologic states such as infection, autoimmune disease or malignancy. Histiocytes in the bone marrow, spleen or lymph nodes become activated to the point that phagocytosis proceeds unchecked. Clinical signs usually present within the first decade and include fever, jaundice, hepatosplenomegaly, lymphadenopathy and skin rash. Prompt initiation of treatment improves survival though prognosis remains poor even with intervention.
Top Hemophagocytic syndrome Doctors on Curofy
Top doctors who continously share their opinions on Hemophagocytic syndromeEx.central Hospital Dhanbad.1985 ..1993..ex.pathologist .drs Tribedy and Roy Dianostic Lab.kolkata.ex Pathologist.inst of Child Health Kolkata.
Senior Pathologist
School of Tropical Medicine. Kolkata
d c p
The Health City Hospital
Intensivist
Maharashtra University of Health Sciences Nashik
bhms
BCCL Hospital
Ex. Dy.Cmo
PMCH
MBBS
Parmarth Homeopathic Ausdhalay
M/O Incherge
Homeopathy University Jaipur
DHMS
Tata Central Hospital, Jamadoba
Consultant Pathologist
SCBMC, Cuttack, Orissa
MD(Pathology)
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