Glioblastoma
The most malignant astrocytic tumor (WHO grade IV). It is composed of poorly differentiated neoplastic astrocytes and it is characterized by the presence of cellular polymorphism, nuclear atypia, brisk mitotic activity, vascular thrombosis, microvascular proliferation and necrosis. It typically affects adults and is preferentially located in the cerebral hemispheres. It may develop from diffuse astrocytoma WHO grade II or anaplastic astrocytoma (secondary glioblastoma, IDH-mutant), but more frequently, it manifests after a short clinical history de novo, without evidence of a less malignant precursor lesion (primary glioblastoma, IDH- wildtype). (Adapted from WHO)
Disease Alternative Name
19 Views
, 2 Answers
37 Views
, 5 Answers
97 Views
, 5 Answers
Thanks for the answers. Admitted and received 2doses of metyl pred, Iv 1gr each. Father of pt is also a doctor. Discussed with others . Majority suggested Stereotactic biopsy which is not available here and hence transferred to near b...
144 Views
, 1 Like
, 7 Answers
Brain edema raised ICP and 2ndary vascular compromise and PCA infarction. Kernohan notch - a radiological findings due to midline shift due to mass effect resulting in compression of contralateral cerebral crust by tentorium cerebelli resu...
170 Views
, 1 Like
, 1 Answer
332 Views
, 1 Like
, 2 Answers
It is high grade glioma, life expectancy is about 1-1.5 yr. Biopsy with chemo/ radio therapy can be given. If deteriorate decompression can be done. Continue antiedema and antiepileptic. Ayushman can be used anywhere in India.
Recent Cases of Glioblastoma
Browse recently discussed Glioblastoma cases by specialistsTop Cases of Glioblastoma
Selected by editors, top cases are known for unique problem or best solutionTop Glioblastoma Doctors on Curofy
Top doctors who continously share their opinions on GlioblastomaKerala Institute of Medical Sciences
Professor and Senior Consultant Neurology
Medical College Thiruvananthapuram
MBBS,MD (Med) ,DM(Neurology),DNB(Neurology), FAAN(Fellow of American Academy of Neurology)
Medical Component OfHCM
Remained Incharge Medical Officer with Hon'Ble C.M of J and K for More Than 20 Years from Jan 2000 To October 2020
Govt. Medical College, Jammu
M.S (General Surgery )
20 Years of Teaching To Both UGs & PGs
As Assistant, Associate & Professor
Gandhi Medical College, Dr. NTRUHS
MD Pathology
Anand Hospital
Neuro Intensive Care
Zhengzhou University
MBBS
PHC Bichpuri and ESI Dispensary Chippitola Agra & SN Medical College Agra & Fatehgarh
Medical Officer Incharge
SN Medical College, Agra
DA
Trending Diseases
Trending Cases
Which of the drugs do you recommend for symptomatic management of fever and pain in children?
Doc Insights11 Likes27 AnswersPlease share your overall clinical experience with the Ibuprofen + Paracetamol combination in treating Paediatric Fever and pain?
Doc Insights7 Likes15 Answers- Login to View the image
A 57 yrs old male patient c/o sudden vision loss/left side weakness/agitated/fever bodyache *Chief Complaints* Sudden vision loss Left side weakness Unable to walk Agitated urge to pee/poop but nothing comes out when he go Bodyache *History* CVA with left hemisphere 3 yrs back K/c/o HTN/DM *Vitals* BP 150/80 Pulse 68 Spo2 98 *Physical Examination* B/L Pupils dilated Left side weakness Chest -B/L clear P/A- soft no any tenderness or distension CNS -Alert and aware Genitals -Normal *Investigations* Attached *Diagnosis* CVA with HTN/DM ?TIA/Retinal detachment *Management* Medically conservative Kindly suggest
Dr. Manoj Kumar0 Like3 Answers Artificial intelligence (AI) in medicine & dentistry have been on the rise in recent years. It has the potential to enhance efficiency, accuracy, and patient outcomes by analyzing data, detecting patterns, and providing outcome to the practitioners. What is your opinion about AI in dentistry?
Dental-Insights2 Likes3 Answers- Login to View the image
Penile fracture or rupture is a rare event but requires urgent diagnosis and intervention. It is a rupture of the penile albuginea of the corpora cavernosa or corpus spongiosum due to trauma to the erect penis, most commonly during sexual intercourse. Dr. Vivek Jha is sharing a clinical case of “Penile Fracture” managed with surgical expertise by him. Share your views on the case & learn new things.
Expert Insights2 Likes2 Answers
88 Views
, 1 Like
, 2 Answers