Dense deposit disease

Proliferative glomerulonephritis characterized by activation of the alternative complement pathway, resulting in mesangial hypercellularity, endocapillary proliferation, and glomerular basement membrane intramembranous highly electron dense deposits.

Disease Alternative Name

membranoproliferative glomerulonephritis type 2

mesangiocapillary glomerulonephritis type 2

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Sonal Gandhi

MBBS Student

Quick review Pathology * Nephrotic syndrome The nephrotic syndrome is characterized by proteinuria, which results in hypoalbuminemia and edema. • Podocyte injury is an underlying mechanism of proteinuria, and may ...See More

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