Langerhans cell histiocytosis

A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs affected at presentation. (WHO, 2001)

Disease Alternative Name

langerhans cell granulomatosis

nos

not otherwise specified

histiocytosis x

lch

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Recent Cases of Langerhans cell histiocytosis

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Concluded Case

Dr. P.kishore Kumar

Dermatology

SWEET'S SYNDROME

50 years male with rheumatoid arthritis, presents with painful papules and nodules on both legs for 2 weeks, associated ...See More

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Dr. P.kishore Kumar

Dermatology

Yes it's SWEET'S SYNDROME..also called Acute febrile neutrophils dermatitis The age, painful lesions on the both legs Here main clinical findings are shor duration of onset of eruptions with fever ..pathological finding is neutrophils i...

Dr. Ammad Ali

Internal Medicine

7 years old female child with history of right ocular eye ball expulsion as shown in figure,she also has swollen right k...See More

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Top Cases of Langerhans cell histiocytosis

Selected by editors, top cases are known for unique problem or best solution

Dr. Ila Jain

Pathology

1. Langerhans cell histiocytosis It is a spectrum of proliferation of immature dendritic cells called langerhans cell. 2. The most common mutation is activating valine to glutamate substitution at residue 600 in BRAF. 3. Clinically man...See More

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Concluded Case

Dr. Mohammed Harris

Pediatrics

1.4 year old FCH a case of bronchopneumonia (typical x-ray ) , was on IV Antibiotics, patent is symptomatically better , Discharged on orally Initial TC - 44000-->33000 --->10000 Platelet. 6lakhs to 8 lakhs HB --> 7.5 ---...See More

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Dr. Nitesh Prasad

MBBS MD DCH/IPPC(Sydney) Dip PAEDIATRICS(ireland royal college) PGPV FPCP PGPN(BOSTON)

Thrombocytosis itself is a marker of sepsis . Plus iron deficiency may contribute to it .acute phase reactants like esr take some time to come to normal . Blood c/s should have been done. Would like to see the X-ray film too.

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