Johnson syndrome
A systemic, serious, and life-threatening disorder characterized by lesions in the skin and mucous membranes that may lead to necrosis. The lesions may appear anywhere in the body but they occur more commonly in the palms, soles, dorsum of the hands, and extensor surfaces. The lesions are vesicular or necrotic in the center, surrounded by an erythematous zone and occupy less than 10% of the body surfaces. The appearance of the mucocutaneous lesions is preceded by an upper respiratory tract infection. It is an immune complex hypersensitivity reaction usually caused by drugs (e.g., sulfa, phenytoin, penicillin), viruses (e.g., herpes simplex, influenza, hepatitis), and malignancies (e.g., carcinoma and lymphoma).
Disease Alternative Name
Recent Cases of Johnson syndrome
Browse recently discussed Johnson syndrome cases by specialistsTop Cases of Johnson syndrome
Selected by editors, top cases are known for unique problem or best solution1223 Views
, 3 Likes
, 52 Answers
Yes this is herpes zoster You rightly put her on acyclovir Kindly give the full doses of 800mg 5times a day and tapper off gradually and keep on maintenance dose don't withdraw immidiately Second thing don't stop steroids as she on Rest loc...
41 Views
, 21 Likes
, 18 Answers
Top Johnson syndrome Doctors on Curofy
Top doctors who continously share their opinions on Johnson syndromeNational Institute of Medical Science
Md Paediatrics
National Institute of Medical Science
MD pediatrics
Siddhivinayak Clinic
Lceh Gp
Trending Cases
Pharma standards body Indian Pharmacopoeia Commission (IPC) has issued an alert over some commonly used medicines as they trigger adverse reactions. Commonly-used painkiller "Nimesulide" & antibiotic "Cefuroxime" can lead to serious skin disorders. In your practice and observation, have you noticed any such adverse reactions in patients in recent times?
Doc Insights0 Like7 Answers- Login to View the image
A patient of 34 years complaining about having itching on the b/l palm region since 7-8 months and it has started from a small black patch . And it spreads in this condition. He has no history of DM and hypertension. N also No ho of smoking n alcohol.
Dr. Veenu Yadav5 Likes7 Answers - Login to View the image
M37yrs. Pain neck referred to both hands. 6 months.
Dr. Syam Sundar Patro2 Likes4 Answers - Login to View the image
F.34yrs. Spot diagnosis please. No h/o Injury.
Dr. Syam Sundar Patro0 Like4 Answers - Login to View the image
Dear doctor friends, Kindly suggest Rx. Female /55 years Diabetic Suffering from GANGRENE RIGHT FOOT *Chief Complaints* Swelling over right foot Bleeding from wound No pus Wound Not getting good *History* Diabetic type 2 *Vitals* PPS 180 BP 120/84 *Physical Examination* Deep bleeding wound but no pus *Investigations* The sonography report is attached *Diagnosis* Gangrene right feet, skin so thickened *Management* Regular dressing, controlled blood sugar, strictly following diet control
Chetna Vora1 Like3 Answers
34 Views
, 5 Likes
, 24 Answers